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uniQure N.V. (QURE)

24.83 -0.47 (-1.86%)
At close: 4:00:01 PM EDT
26.56 +1.73 (+6.97%)
After hours: 7:12:25 PM EDT
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What's happening with QURE?

12m ago
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uniQure faces a concentrated regulatory test around AMT-130, its Huntington’s disease gene therapy. Recent commentary highlights uncertainty over four-year durability data and a reported securities investigation, while the company’s next scheduled event is its November 4, 2026third-quarter earnings report. QURE is down 1.86% in the current regular session.

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  • Previous Close 25.30
  • Open 25.11
  • Bid 18.02 x 200
  • Ask 30.29 x 200
  • Day's Range 23.56 - 25.20
  • 52 Week Range 8.73 - 68.62
  • Volume 1,821,654
  • Avg. Volume 1,993,165
  • Market Cap (intraday) 1.722B
  • Beta (5Y Monthly) 1.06
  • PE Ratio (TTM) --
  • EPS (TTM) -4.03
  • Earnings Date Nov 4, 2026
  • Forward Dividend & Yield -- (0.00%)
  • 1y Target Est 60.16
  • Motley Fool Rating Bearish

uniQure N.V. develops treatments for patients suffering from rare and other devastating diseases in the United States. The company offers HEMGENIX that allows people living with hemophilia B to produce factor IX, which can lower the risk of bleeding. Its lead product candidate is AMT-130, a gene therapy candidate, which is in Phase I/II clinical study for the treatment of Huntington's disease. The company also develops AMT-260, which is in Phase I/IIa clinical trial for the treatment of mesial temporal lobe epilepsy; AMT-162, which is in Phase I/IIa clinical trial to treat superoxide dismutase enzyme-amyotrophic lateral sclerosis; and AMT-191, an investigational gene therapy candidate which is in phase I/IIa clinical trial for the treatment of fabry disease. It has a licensing agreement with Apic Bio to develop, manufacture, and commercialize intrathecally administered investigational gene therapy for ALS caused by mutations in SOD-1; and development and commercial supply agreement with CLS Bhering. uniQure N.V. was founded in 1998 and is headquartered in Amsterdam, the Netherlands.

www.uniqure.com

221

Full Time Employees

December 31

Fiscal Year Ends

Healthcare

Sector

Biotechnology

Industry

Performance Overview

Trailing total returns as of 10/30/2026, which may include dividends or other distributions. Benchmark is S&P 500 (^GSPC) .

YTD Return

QURE
3.76%
S&P 500 (^GSPC)
10.73%

1-Year Return

QURE
63.41%
S&P 500 (^GSPC)
11.11%

3-Year Return

QURE
337.15%
S&P 500 (^GSPC)
81.91%

5-Year Return

QURE
18.51%
S&P 500 (^GSPC)
64.59%

Earnings Trends

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Earnings Per Share

GAAP
Normalized
GAAP
Normalized

Revenue vs. Earnings

Annual
Quarterly
Annual
Quarterly
Q2 FY26
Revenue 5.13M
Earnings -71.14M
Profit Margin -1,387.76%

Q3

FY25

Q4

FY25

Q1

FY26

Q2

FY26

-60M
-40M
-20M
0
-2000.0%
-1500.0%
-1000.0%

Analyst Insights

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Top Analyst

Chardan Capital
64/100
Latest Rating
Buy

Analyst Price Targets

27.89
60.16 Average
24.83 Current
91.20 High

Analyst Recommendations

  • Strong Buy
  • Buy
  • Hold
  • Underperform
  • Sell

Latest Rating

Date 10/5/2026
Analyst Barclays
Rating Action Downgrade
Rating Equal-Weight
Price Action Lowers
Price Target 60 -> 28

Statistics

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Valuation Measures

Annual
As of 10/29/2026
  • Market Cap

    1.75B

  • Enterprise Value

    1.01B

  • Trailing P/E

    --

  • Forward P/E

    --

  • PEG Ratio (current)

    --

  • Price/Sales (ttm)

    84.63

  • Price/Book (mrq)

    5.41

  • Enterprise Value/Revenue

    53.92

  • Enterprise Value/EBITDA

    --

Financial Highlights

Profitability and Income Statement

  • Profit Margin

    0.00%

  • Return on Assets (ttm)

    -15.72%

  • Return on Equity (ttm)

    -157.61%

  • Revenue (ttm)

    18.67M

  • Net Income Avi to Common (ttm)

    -252.21M

  • Diluted EPS (ttm)

    -4.03

Balance Sheet and Cash Flow

  • Total Cash (mrq)

    810.33M

  • Total Debt/Equity (mrq)

    170.40%

  • Levered Free Cash Flow (ttm)

    -77.58M

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Company Insights

Fair Value

24.83 Current

Dividend Score

0 Low
Sector Avg.
100 High

Hiring Score

0 Low
Sector Avg.
100 High

Insider Sentiment Score

0 Low
Sector Avg.
100 High

Research Reports

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  • Lowering target price to $8.00

    UNIQURE NV has an Investment Rating of HOLD; a target price of $8.000000; an Industry Subrating of Medium; a Management Subrating of Medium; a Safety Subrating of Medium; a Financial Strength Subrating of Medium; a Growth Subrating of Low; and a Value Subrating of Low.

  • What does Argus have to say about QURE?

    UNIQURE NV has an Investment Rating of HOLD; a target price of $9.000000; an Industry Subrating of Medium; a Management Subrating of Medium; a Safety Subrating of Medium; a Financial Strength Subrating of Medium; a Growth Subrating of Low; and a Value Subrating of High.

  • What does Argus have to say about QURE?

    UNIQURE NV has an Investment Rating of HOLD; a target price of $9.000000; an Industry Subrating of Medium; a Management Subrating of Medium; a Safety Subrating of Medium; a Financial Strength Subrating of Medium; a Growth Subrating of Low; and a Value Subrating of High.

  • Lowering target price to $9.00

    UNIQURE NV has an Investment Rating of HOLD; a target price of $9.000000; an Industry Subrating of Medium; a Management Subrating of Medium; a Safety Subrating of Medium; a Financial Strength Subrating of Medium; a Growth Subrating of Medium; and a Value Subrating of Low.

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