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Summit Therapeutics Inc. (SMMT)

17.61 +0.48 (+2.77%)
At close: September 4 at 4:00:00 PM EDT
17.63 +0.02 (+0.12%)
After hours: September 4 at 7:59:13 PM EDT
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Summit Therapeutics is gaining attention due to promising Phase III trial results for ivonescimab, its lead cancer drug, particularly in lung and biliary cancers. With a pivotal FDA decision expected by mid-November 2026, the company faces both significant opportunities and execution risks.

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  • Previous Close 17.13
  • Open 16.93
  • Bid 12.56 x 200
  • Ask 14.55 x 200
  • Day's Range 16.80 - 17.63
  • 52 Week Range 12.07 - 29.23
  • Volume 6,221,179
  • Avg. Volume 5,301,803
  • Market Cap (intraday) 14.044B
  • Beta (5Y Monthly) -1.24
  • PE Ratio (TTM) --
  • EPS (TTM) -1.11
  • Earnings Date (est.) Oct 19, 2026
  • Forward Dividend & Yield --
  • Ex-Dividend Date --
  • 1y Target Est 28.39

Summit Therapeutics Inc., a biopharmaceutical company, focuses on discovery, development, and commercialization of patient, physician, caregiver, and societal friendly medicinal therapies. Its lead development candidate is ivonescimab, a bispecific antibody for immunotherapy through blockade of PD-1 with the anti-angiogenesis for the treatment of non-small lung cancer (NSCLC) and colorectal cancer (CRC). The company has also combined ivonescimab with chemotherapy, which is in phase III clinical trial for the patients with epidermal growth factor receptor, mutated, and locally advanced or metastatic non-squamous NSCLC; first-line metastatic NSCLC; and first-line unresectable metastatic CRC. It markets its products in the United states, Canada, Europe, Japan, Latin America, Middle East, and Africa. The company was founded in 2003 and is headquartered in Miami, Florida.

www.smmttx.com

265

Full Time Employees

December 31

Fiscal Year Ends

Healthcare

Sector

Biotechnology

Industry

Performance Overview

Trailing total returns as of 9/4/2026, which may include dividends or other distributions. Benchmark is S&P 500 (^GSPC) .

YTD Return

SMMT
0.66%
S&P 500 (^GSPC)
12.75%

1-Year Return

SMMT
26.03%
S&P 500 (^GSPC)
18.71%

3-Year Return

SMMT
980.06%
S&P 500 (^GSPC)
70.93%

5-Year Return

SMMT
139.20%
S&P 500 (^GSPC)
70.18%

Earnings Trends

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Earnings Per Share

GAAP
Normalized
GAAP
Normalized

Revenue vs. Earnings

Annual
Quarterly
Annual
Quarterly
Q2 FY26
Revenue --
Earnings -215.7M
Profit Margin 0.00%

Q3

FY25

Q4

FY25

Q1

FY26

Q2

FY26

-200M
-150M
-100M
-50M
0
0.0%

Analyst Insights

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Top Analyst

Stifel
76/100
Latest Rating
Buy

Analyst Price Targets

10.98 Low
28.39 Average
17.60 Current
41.65 High

Analyst Recommendations

  • Strong Buy
  • Buy
  • Hold
  • Underperform
  • Sell

Latest Rating

Date 8/26/2026
Analyst HC Wainwright & Co.
Rating Action Reiterates
Rating Neutral
Price Action --
Price Target --

Statistics

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Valuation Measures

Annual
As of 9/1/2026
  • Market Cap

    11.30B

  • Enterprise Value

    10.63B

  • Trailing P/E

    --

  • Forward P/E

    --

  • PEG Ratio (5yr expected)

    --

  • Price/Sales (ttm)

    --

  • Price/Book (mrq)

    17.93

  • Enterprise Value/Revenue

    --

  • Enterprise Value/EBITDA

    --

Financial Highlights

Profitability and Income Statement

  • Profit Margin

    0.00%

  • Return on Assets (ttm)

    -101.61%

  • Return on Equity (ttm)

    -192.51%

  • Revenue (ttm)

    --

  • Net Income Avi to Common (ttm)

    -856.09M

  • Diluted EPS (ttm)

    -1.11

Balance Sheet and Cash Flow

  • Total Cash (mrq)

    690.68M

  • Total Debt/Equity (mrq)

    3.24%

  • Levered Free Cash Flow (ttm)

    -139.68M

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Company Insights

Fair Value

17.60 Current

Dividend Score

0 Low
Sector Avg.
100 High

Hiring Score

0 Low
Sector Avg.
100 High

Insider Sentiment Score

0 Low
Sector Avg.
100 High

Research Reports

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  • Daily – Vickers Top Buyers & Sellers for 06/15/2026

    The Vickers Top Buyers & Sellers is a daily report that identifies the five companies the largest insider purchase transactions based on the dollar value of the transactions as well as the five companies the largest insider sales transactions based on the dollar value of the transactions.

  • Daily – Vickers Top Buyers & Sellers for 06/05/2026

    The Vickers Top Buyers & Sellers is a daily report that identifies the five companies the largest insider purchase transactions based on the dollar value of the transactions as well as the five companies the largest insider sales transactions based on the dollar value of the transactions.

  • Daily – Vickers Top Buyers & Sellers for 09/12/2025

    The Vickers Top Buyers & Sellers is a daily report that identifies the five companies the largest insider purchase transactions based on the dollar value of the transactions as well as the five companies the largest insider sales transactions based on the dollar value of the transactions.

  • Daily – Vickers Top Buyers & Sellers for 03/28/2024

    The Vickers Top Buyers & Sellers is a daily report that identifies the five companies the largest insider purchase transactions based on the dollar value of the transactions as well as the five companies the largest insider sales transactions based on the dollar value of the transactions.

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