
Alnylam Pharmaceuticals, Inc. (ALNY)
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Learn more- Previous Close
309.49 - Open
308.85 - Bid 295.76 x 200
- Ask 296.36 x 100
- Day's Range
295.79 - 311.88 - 52 Week Range
245.96 - 495.55 - Volume
1,115,819 - Avg. Volume
1,236,165 - Market Cap (intraday)
39.514B - Beta (5Y Monthly) --
- PE Ratio (TTM)
74.59 - EPS (TTM)
3.97 - Earnings Date (est.) Jul 30, 2026
- Forward Dividend & Yield --
- Ex-Dividend Date --
- 1y Target Est
449.48
Recent News: ALNY
View MorePerformance Overview: ALNY
Trailing total returns as of 5/1/2026, which may include dividends or other distributions. Benchmark is S&P 500 (^GSPC) .
YTD Return
1-Year Return
3-Year Return
5-Year Return
Earnings Trends: ALNY
View MoreAnalyst Insights: ALNY
View MoreStatistics: ALNY
View MoreValuation Measures
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Market Cap
39.51B
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Enterprise Value
37.78B
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Trailing P/E
74.40
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Forward P/E
33.11
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PEG Ratio (5yr expected)
0.59
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Price/Sales (ttm)
9.45
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Price/Book (mrq)
36.74
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Enterprise Value/Revenue
8.81
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Enterprise Value/EBITDA
43.64
Financial Highlights
Profitability and Income Statement
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Profit Margin
12.55%
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Return on Assets (ttm)
10.06%
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Return on Equity (ttm)
90.36%
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Revenue (ttm)
4.29B
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Net Income Avi to Common (ttm)
537.99M
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Diluted EPS (ttm)
3.97
Balance Sheet and Cash Flow
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Total Cash (mrq)
3.01B
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Total Debt/Equity (mrq)
276.20%
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Levered Free Cash Flow (ttm)
191.27M
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Company Insights: ALNY
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Insider Sentiment Score
Research Reports: ALNY
View More-
Alnylam Earnings: Amvuttra Uptake Drives Sales; Durability of Demand in Focus Amid Competition
Alnylam Pharmaceuticals is a leader in the study of RNA interference (RNAi) therapeutics. RNAi is a naturally occurring biological pathway within cells for sequence-specific silencing and regulation of gene expression. Alnylam’s commercial RNAi therapeutic products include Onpattro and Amvuttra (for hATTR amyloidosis), Givlaari (for acute hepatic porphyria), and Oxlumo (for primary hyperoxaluria type 1), all developed and commercialized by Alnylam. Plus, Leqvio (for hypercholesterolemia) and Qfitlia (for hemophilia A or B), which are being commercialized by Alnylam’s partners, Novartis and Sanofi, respectively. It also has several clinical programs across various therapeutic areas, including cardio-metabolic diseases, neuroscience, and hematology.
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Narrow-Moat Alnylam's Growth Driven By Strong Demand For Amvuttra in ATTR-CM
Alnylam Pharmaceuticals is a leader in the study of RNA interference (RNAi) therapeutics. RNAi is a naturally occurring biological pathway within cells for sequence-specific silencing and regulation of gene expression. Alnylam’s commercial RNAi therapeutic products include Onpattro and Amvuttra (for hATTR amyloidosis), Givlaari (for acute hepatic porphyria), and Oxlumo (for primary hyperoxaluria type 1), all developed and commercialized by Alnylam. Plus, Leqvio (for hypercholesterolemia) and Qfitlia (for hemophilia A or B), which are being commercialized by Alnylam’s partners, Novartis and Sanofi, respectively. It also has several clinical programs across various therapeutic areas, including cardio-metabolic diseases, neuroscience, and hematology.
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Daily – Vickers Top Buyers & Sellers for 02/18/2026
The Vickers Top Buyers & Sellers is a daily report that identifies the five companies the largest insider purchase transactions based on the dollar value of the transactions as well as the five companies the largest insider sales transactions based on the dollar value of the transactions.
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Alnylam Earnings: Milestone Year as Firm Turned Profitable; Demand for Amvuttra Drives Growth
Alnylam Pharmaceuticals is a leader in the study of RNA interference (RNAi) therapeutics. RNAi is a naturally occurring biological pathway within cells for sequence-specific silencing and regulation of gene expression. Alnylam has five drugs on the market: Onpattro and Amvuttra for hATTR amyloidosis, Givlaari for acute hepatic porphyria, Oxlumo for primary hyperoxaluria type 1, and Leqvio for hypercholesterolemia. It also has several clinical programs across various therapeutic areas: genetic medicines; cardio-metabolic diseases; hepatic infectious diseases, and CNS/ocular diseases. Upfront fees from research partnerships have boosted Alnylam's cash levels, and the company stands to see additional milestones and royalties from drugs commercialized under collaboration partnerships.
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